This patient care pathway provides steps and online resources — from initial assessment of need to transition to home — for patients who may require parenteral nutrition (PN). Click on resources to pull up documents, checklists, and websites. Please note that, though the majority of these materials are open-source, some require a subscription in order to obtain access to full journal articles.
This pathway was developed by the ASPEN PN Safety Committee.

- Determine if patient is an appropriate candidate for PN
- Determine nutrient and therapy goals
- Assess if patient has appropriate venous access in place
- Use Computerized Provider Order Entry (CPOE) when able
- Use Clinical Decision Support tools
- Communicate PN prescription to pharmacy using electronic means with minimal transcription
- Clinical review
- Pharmacologic review
- Communication and order modification with prescriber as needed
- Initiate PN administration using PN Administration Checklist
- Initiate monitoring protocol
- Evaluate efficacy and goals of therapy
- Verify insurance coverage and identify home infusion provider
- Educate patient and caregivers on home PN and supports
- Identify prescriber
- Communicate discharge PN order, labs, frequency and monitoring parameters to home infusion company
- Develop error reporting program
- Implement infection control for CLABSI
- Monitor appropriate PN use
- Maintain glucose control
- Monitor readmissions of home PN patients